Mitf ELISA Kit for Mouse(Mus musculus) | EIAab.comMitf ELISA Kit for Mouse(Mus musculus)

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Mitf (Gene name),

Microphthalmia-associated transcription factor (Protein name ), MITF_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mitf(Bw;Mi;Vit);

Protein name:

Microphthalmia-associated transcription factor;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA in the form of homodimer or heterodimer with either TFE3, TFEB or TFEC. Interacts with KARS.

Function:

Transcription factor for tyrosinase and tyrosinase-related protein 1. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

526

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

526:

SSVSPGASKT | SSRRSSMSAE | ETEHAC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF11851

UniGene:

Mm.333284

KEGG:

mmu:17342

String:

Q08874

SMR:

Q08874

Uniprot:

Q08874

FOR

ELISA Kit for Mouse Microphthalmia-associated transcription factor

Cat.:

E0547m

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Microphthalmia-associated transcription factor

Cat.:

E0547h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Microphthalmia-associated transcription factor

Cat.:

E0547r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Microphthalmia-associated transcription factor

Cat.:

U0547r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Microphthalmia-associated transcription factor

Cat.:

U0547h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Microphthalmia-associated transcription factor

Cat.:

U0547m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Microphthalmia-associated transcription factor

Cat.:

P0547Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Microphthalmia-associated transcription factor

Cat.:

P0547Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Microphthalmia-associated transcription factor

Cat.:

P0547Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Microphthalmia-associated transcription factor

Protein for Mouse Microphthalmia-associated transcription factor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein."
Hodgkinson C.A. , Moore K.J. , Nakayama A. , Steingrimsson E. , Copeland N.G. , Jenkins N.A. , Arnheiter H.
Cell74:395-404(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS M AND M1);VARIANTS MI AND MI-WS;TISSUE SPECIFICITY
tissue: Melanocyte.
2.

"Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus."
Hallsson J.H. , Favor J. , Hodgkinson C. , Glaser T. , Lamoreux M.L. , Magnusdottir R. , Gunnarsson G.J. , Sweet H.O. , Copeland N.G. , Jenkins N.A. , Steingrimsson E.
Genetics155:291-300(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING;MUTAGENESIS
strain: 129/Sv.
tissue: Heart.
3.

Hallsson J.H. , Favor J. , Hodgkinson C. , Glaser T. , Lamoreux M.L. , Magnusdottir R. , Gunnarsson G.J. , Sweet H.O. , Copeland N.G. , Jenkins N.A. , Steingrimsson E.
Submitted (2004-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 41; 48; 52 AND 91
4.

"Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences."
Steingrimsson E. , Moore K.J. , Lamoreux M.L. , Ferre-D'Amare A.R. , Burley S.K. , Sanders Zimring D.C. , Skow L.C. , Hodgkinson C.A. , Arnheiter H. , Copeland N.G. , Jenkins N.A.
Nat. Genet.8:256-263(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS H AND M);VARIANTS
strain: C57BL/6.
tissue: Heart.
tissue: Melanocyte.
5.

"A helix-loop-helix transcription factor-like gene is located at the mi locus."
Hughes M.J. , Lingrel J.B. , Krakowsky J.M. , Anderson K.P.
J. Biol. Chem.268:20687-20690(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 345-392
strain: C57BL/6.
tissue: Heart.
6.

"Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium."
Amae S. , Fuse N. , Yasumoto K. , Sato S. , Yajima I. , Yamamoto H. , Udono T. , Durlu Y.K. , Tamai M. , Takahashi K. , Shibahara S.
Biochem. Biophys. Res. Commun.247:710-715(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
7.

"The recessive phenotype displayed by a dominant negative microphthalmia-associated transcription factor mutant is a result of impaired nucleation potential."
Takebayashi K. , Chida K. , Tsukamoto I. , Morii E. , Munakata H. , Arnheiter H. , Kuroki T. , Kitamura Y. , Nomura S.
Mol. Cell. Biol.16:1203-1211(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
8.

"The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells."
Lee Y.N. , Nechushtan H. , Figov N. , Razin E.
Immunity20:145-151(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KARS
9.

"An L1 element intronic insertion in the black-eyed white (Mitfmi-bw) gene: the loss of a single Mitf isoform responsible for the pigmentary defect and inner ear deafness."
Yajima I. , Sato S. , Kimura T. , Yasumoto K. , Shibahara S. , Goding C.R. , Yamamoto H.
Hum. Mol. Genet.8:1431-1441(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MI-BW

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